Really well drawn. Sometimes funny, sometimes more serious. Updated monthly.
http://www.boltcity.net/copper_home.htm
Funny British comic. Really quite funny.
http://www.scarygoround.com/
Crass humor. Not for kiddies though it's drawn like it.
http://www.little-gamers.com/
Weird. Funny. Sometimes more one that the other. I've read up through part of day four.
http://www.wigu.com/
Good for a grin. Sometimes even a chuckle. Definitely worth a daily read.
http://www.reallifecomics.com/
American Manga. Well drawn. First hundred or so are pretty good. The pacing has gotten pretty slow lately so I usually wait a while and read a couple of months worth in one go.
http://www.megatokyo.com/
Funnies. Family friendly. About a game review publishing company. Mostly not about games, though.
http://www.pvponline.com/
Hilarious. Largely revolves around gaming. Occasionally violent and crude. Always on point.
http://www.penny-arcade.com/